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What is this medicine
Xenical blocks absorption of dietary fat into the bloodstream, thereby reducing the number of calories you get from a meal. At the usual dosage level, it cuts fat absorption by almost one-third. Combi ned with a low-calorie diet, it is used to promote weight loss and discourage the return of unwanted pounds.

The drug is prescribed for the frankly obese and for merely overweight people who have other health problems such as high blood pressure, diabetes, or high cholesterol levels. Your weight status is determined by your body mass index (BMI), a comparison of height to weight.

How should you take this medication?
Xenical comes as a capsule to take by mouth. It is usually taken three times a day with each main meal that contains fat. Each time you take Xenical, your meal should contain no more than about 30% of calories from fat. Take Xenical during or up to 1 hour after a meal. If a meal is missed or does not have fat, you may skip your dose. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Xenical is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being absorbed and disgested. This undigested fat is then removed in your bowel movements (BM).

What special precautions should I follow?
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

For patients with diabetes: Weight loss may result in an improvement in your condition, and your doctor may need to change your dose of oral diabetes medicine or insulin.

Overdosage
There is no report for massive overdose of Xenical. Although the drug seems relatively harmless, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention.

What special dietary instructions should I follow?
To help you get started on reducing the fat in your diet to about 30%, read the labels on all the foods you buy. While you are taking Xenical, you should avoid foods that have more than 30% fat. When eating meat, poultry (chicken) or fish, eat only 2 or 3 ounces (about the size of a deck of cards). Choose lean cuts of meat and remove the skin from poultry. Fill up your meal plate with more grains, fruits, and vegetables. Replace whole-milk products with nonfat or 1% milk and reduced- or low-fat dairy items. Cook with less fat. Use vegetable oil spray when cooking. Salad dressings; many baked i tems; and prepackaged, processed, and fast foods are usually high in fat. Use the low- or non-fat versions of these foods and/or cut back on serving sizes.

What side effects may occur?
The most common side effect of Xenical is changes in bowel movement (BM) habits. This generally occurs during the first weeks of treatment; however, it may continue throughout your use of Xenical. Tel l your doctor if any of these symptoms are severe or do not go away:

- oily, spotting BMs
- gas with discharge
- urgent need to have a BM
- oily or fatty stools
- an oily discharge
- increased number of BMs
- inability to control BMs
- orange or brown color of a BM
- stomach pain
-

If you experience any of the following symptoms, cal l your doctor immediately:

- itching
- redness of skin
- skin rash or hives
- swelling
- chest pain
- difficulty breathing
- fever




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